To escape or disappear. (Not necessarily in a southerly direction.)
She got on her bike and decided to head south.
by eskimokahoona April 6, 2016
while giving oral sex to your partner you start licking their asshole
she was heading south on me
by Anonymous November 3, 2003
"best keep out of her way, the red army are heading south!"
by Dr Baz October 7, 2003